Latest Publications
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A pilot study of genomic-guided induction therapy followed by immunotherapy with difluoromethylornithine maintenance for high-risk neuroblastoma
Jacqueline M. Kraveka, Elizabeth C. Lewis, Genevieve Bergendahl, William Ferguson, Javier Oesterheld, Elizabeth Kim, Abhinav B. Nagulapally, Karl J. Dykema, Valerie I. Brown, William D. Roberts, Deanna Mitchell,on E Dslin, Derek Hanson, Michael S. Isakoff,[...]
Identification of Let-7 miRNA Activity as a Prognostic Biomarker of SHH Medulloblastoma
Maximillian S Westphal 1, Eunjee Lee 1 2, Eric E Schadt 1 2, Giselle S Sholler 3 4, Jun Zhu, Identification of Let-7 miRNA Activity as a Prognostic Biomarker of SHH Medulloblastoma, Cancers (Basel). 2021 Dec[...]
Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion
Sara A. Byron*, William P. D. Hendricks*, Abhinav B. Nagulapally*, Jacqueline M. Kraveka, William S. Ferguson, Valerie I. Brown, Don E. Eslin, Deanna Mitchell, Albert Cornelius, William Roberts, Michael S. Isakoff, Javier E. Oesterheld, Randal[...]
The MDM2 inhibitor CGM097 combined with the BET inhibitor OTX015 induces cell death and inhibits tumor growth in models of neuroblastoma
Tyler Maser, Joseph Zagorski, Shannon Kelly, Anna Ostrander, Austin Goodyke, Abhinav Nagulapally, Jeffrey Bond, Yeonhee Park, Giselle Saulnier Sholler, The MDM2 inhibitor CGM097 combined with the BET inhibitor OTX015 induces cell death and inhibits tumor growth[...]
Multiple antibodies targeting tumor-specific mutations redirect immune cells to inhibit tumor growth and increase survival in experimental animal models
Shukla, G.S., S.C. Pero, Y. Sun, L. Mei, F. Zhang, G. Sholler, and D.N. Krag, Multiple antibodies targeting tumor-specific mutations redirect immune cells to inhibit tumor growth and increase survival in experimental animal models. Clin Transl Oncol,[...]
Cell surface vimentin-positive circulating tumor cell-based relapse prediction in a long-term longitudinal study of postremission neuroblastoma patients
Izhar S. Batth, Long Dao, Arun Satelli, Abhisek Mitra, Sofia Yi, Hyangsoon Noh, Heming Li, Zachary, Brownlee, Shouhao Zhou, Jeffrey Bond, Jing Wang, Jonathan Gill, Giselle S. Sholler, Shulin Li, Cell surface vimentin-positive circulating tumor cell-based[...]
In The Press
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On-Going Research
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Discover The Future
We are a multi-disciplinary laboratory committed to focussed and efficient drug discovery.