Latest Publications
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Antitumor activity of nifurtimox is enhanced with tetrathiomolybdate in medulloblastoma
Koto K, Lescault P, Brard L, Kim K, Singh R, Bond J, Illenye S, Slavik M, Ashikaga T, Saulnier Sholler G. Antitumor activity of nifurtimox is enhanced with tetrathiomolybdate in medulloblastoma. Int J Oncol. 2011, 38:1329-1341.
Oral RKS262 Reduces Tumor Burden in a Neuroblastoma (NB) Xenograft Animal Model and Mediates Cytotoxicity through SAPK/JNK and ROS Activation in Vitro
Singh R, Dorf L, DeMartino A, Illenye S, Koto K, Ashikaga T, Kwang Kim K, Brard L, Saulnier Sholler G. Oral RKS262 Reduces Tumor Burden in a Neuroblastoma (NB) Xenograft Animal Model and Mediates Cytotoxicity through[...]
A Phase I Study of Nifurtimox in Patients with Relapsed/Refractory Neuroblastoma
Saulnier Sholler G, Bergendahl G, Brard L, Singh AP, Heath B, Bingham P, Ashikaga T, Kamen B, Homans A, Slavik M, Lenox S, Higgins T, Ferguson W. A Phase I Study of Nifurtimox in Patients with[...]
Chemotherapeutic effect of calcidiol derivative B3CD in a neuroblastoma xenograft model. Chem Biol Drug
Lange TS, Zou Y, Singh RK, Kim KK, Kristjansdottir K, Sholler GL, Brard L. Chemotherapeutic effect of calcidiol derivative B3CD in a neuroblastoma xenograft model. Chem Biol Drug Des. 2010 Aug;76(2):164-73. doi: 10.1111/j.1747-0285.2010.00988.x. Epub 2010 May 11. PubMed[...]
Nifurtimox induces apoptosis of neuroblastoma cells in vitro and in vivo
Saulnier Sholler G, Brard L, Straub J, Dorf L, Illyene S, Kalkunte S, Nishi R. Nifurtimox induces apoptosis of neuroblastoma cells in vitro and in vivo. JPHO, 2009 Mar;31(3):187-93.
Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells
Brard L, Singh RK, Kim KK, Lange TS, Saulnier Sholler G Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells. Drug Des Devel Ther. 2009 Feb 6;2:61-9.
In The Press
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On-Going Research
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Discover The Future
We are a multi-disciplinary laboratory committed to focussed and efficient drug discovery.