Latest Publications
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Oral RKS262 Reduces Tumor Burden in a Neuroblastoma (NB) Xenograft Animal Model and Mediates Cytotoxicity through SAPK/JNK and ROS Activation in Vitro
Singh R, Dorf L, DeMartino A, Illenye S, Koto K, Ashikaga T, Kwang Kim K, Brard L, Saulnier Sholler G. Oral RKS262 Reduces Tumor Burden in a Neuroblastoma (NB) Xenograft Animal Model and Mediates Cytotoxicity through[...]
A Phase I Study of Nifurtimox in Patients with Relapsed/Refractory Neuroblastoma
Saulnier Sholler G, Bergendahl G, Brard L, Singh AP, Heath B, Bingham P, Ashikaga T, Kamen B, Homans A, Slavik M, Lenox S, Higgins T, Ferguson W. A Phase I Study of Nifurtimox in Patients with[...]
Chemotherapeutic effect of calcidiol derivative B3CD in a neuroblastoma xenograft model. Chem Biol Drug
Lange TS, Zou Y, Singh RK, Kim KK, Kristjansdottir K, Sholler GL, Brard L. Chemotherapeutic effect of calcidiol derivative B3CD in a neuroblastoma xenograft model. Chem Biol Drug Des. 2010 Aug;76(2):164-73. doi: 10.1111/j.1747-0285.2010.00988.x. Epub 2010 May 11. PubMed[...]
Nifurtimox induces apoptosis of neuroblastoma cells in vitro and in vivo
Saulnier Sholler G, Brard L, Straub J, Dorf L, Illyene S, Kalkunte S, Nishi R. Nifurtimox induces apoptosis of neuroblastoma cells in vitro and in vivo. JPHO, 2009 Mar;31(3):187-93.
Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells
Brard L, Singh RK, Kim KK, Lange TS, Saulnier Sholler G Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells. Drug Des Devel Ther. 2009 Feb 6;2:61-9.
Effect of Indole Ethyl Isothiocyanates on Proliferation, Apoptosis and MAPK Signaling in Neuroblastoma Cell Lines
Singh R, Lange TS, Kim K, Zou Y, Lieb C, Saulnier Sholler G, Brard L. Effect of Indole Ethyl Isothiocyanates on Proliferation, Apoptosis and MAPK Signaling in Neuroblastoma Cell Lines. Bioorg Med Chem Lett. 2007 17(21):5846-5852.
In The Press
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On-Going Research
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