Latest Publications
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Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells
Brard L, Singh RK, Kim KK, Lange TS, Saulnier Sholler G Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells. Drug Des Devel Ther. 2009 Feb 6;2:61-9.
Effect of Indole Ethyl Isothiocyanates on Proliferation, Apoptosis and MAPK Signaling in Neuroblastoma Cell Lines
Singh R, Lange TS, Kim K, Zou Y, Lieb C, Saulnier Sholler G, Brard L. Effect of Indole Ethyl Isothiocyanates on Proliferation, Apoptosis and MAPK Signaling in Neuroblastoma Cell Lines. Bioorg Med Chem Lett. 2007 17(21):5846-5852.
Anti-proliferative and Pro-apoptotic Properties of 3-Bromoacetoxy Calcidiol (B3CD) in High-Risk Neuroblastoma
Lange TS, Singh RK, Kim K, Zou Y, Kalkunte S, Saulnier Sholler G, Swamy N, Brard L*. Anti-proliferative and Pro-apoptotic Properties of 3-Bromoacetoxy Calcidiol (B3CD) in High-Risk Neuroblastoma. Chem Biol Drug Des. 2007 70:302-310
Embryonic sympathoblasts transiently express TrkB in vivo and proliferate in response to brain-derived neurotrophic factor in vitro
Straub J, Saulnier Sholler G, Nishi R, Embryonic sympathoblasts transiently express TrkB in vivo and proliferate in response to brain-derived neurotrophic factor in vitro. BMC Developmental Biology 2007, 7:10
Anti-Tumor activity of Nifurtimox observed in a patient with Neuroblastoma
Saulnier Sholler G, Kalkunte S, Greenlaw C, McCarten K, Forman, E, Anti-Tumor activity of Nifurtimox observed in a patient with Neuroblastoma. J Pediatr Hematol Oncol. 2006; 10:693-695
Advanced Small Cell Carcinoma of the Ovary in a Pediatric Patient with Long-Term Survival and Review of the Literature
Saulnier Sholler G, Luks F, Mangray S, Meech SJ. Advanced Small Cell Carcinoma of the Ovary in a Pediatric Patient with Long-Term Survival and Review of the Literature. J Pediatr Hematol Oncol. 2005;27:169-172
In The Press
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On-Going Research
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Discover The Future
We are a multi-disciplinary laboratory committed to focussed and efficient drug discovery.