Sustained Clinical Response to Treatment Directed by Genomic Expression Profiling Suggests mTOR Signaling is an Effective Target in Choroid Plexus Carcinoma
Cornelius A, Foley J, Mitchell D, Nagulapally A, Bond J, Huntelman M, Corneveaux J, Trent J, Saulnier Sholler G. Sustained Clinical Response to Treatment Directed by Genomic Expression Profiling Suggests mTOR[...]
Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma
Lozier AM, Rich ME, Grawe AP, Peck AS, Zhao P, Ting-Tung Chang, Bond JP, Saulnier Sholler G, Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma. Oncotarget 6(1):[...]
A Feasibility Trial using Molecular-Guided Therapy for the Treatment of Patients with Refractory or Recurrent Neuroblastoma
Saulnier Sholler G, Bergendahl G, Vander Werff A, Ferguson W, Roberts W, Eslin D, Kraveka J, Kaplan J, Mitchell D, Parikh N, Neville K, Ashikaga T, Bond J, Hanna G,[...]
PCI-24781 (abexinostat), a novel histone deacetylase inhibitor, induces reactive oxygen species-dependent apoptosis and is synergistic with bortezomib in neuroblastoma
Saulnier Sholler G, Currier E, Dutta A, Slavik M, Illenye S, Mendonca MC, Dragon J, Roberts S, Bond JP, PCI-24781 (abexinostat), a novel histone deacetylase inhibitor, induces reactive oxygen species-dependent apoptosis[...]
Nifurtimox and radiation combination increases reactive oxygen species and induces apoptosis in medulloblastoma cells
Saulnier Sholler G, Eslin D. Nifurtimox and radiation combination increases reactive oxygen species and induces apoptosis in medulloblastoma cells. American Association for Cancer Research Pediatric Cancer at the Crossroads: Translating Discovery into[...]
DFMO treatment affects the LIN28/Let-7 axis resulting in reduced glycolytic metabolism in Neuroblastoma
Kendzicky A, Rich M, Peck A, Zhao P, VanSickle E, McClung H, Chang A, Saulner Sholler G. DFMO treatment affects the LIN28/Let-7 axis resulting in reduced glycolytic metabolism in Neuroblastoma. American[...]
Mentoring in pediatric oncology: a report from the Children’s Oncology Group Young Investigator Committee
Levy AS1, Pyke-Grimm KA, Lee DA, Palla SL, Naranjo A, Saulnier Sholler G, Gratias E, Maloney K, Parshankar F, Lee-Scott M, Beierle EA, Gow K, Kim GE, Hunger S, Smith[...]
Phase I study of vinblastine and sirolimus in pediatric patients with recurrent or refractory solid tumors
Morgenstern DA, Marzouki M, Bartels U, Irwin MS, Sholler GL, Gammon J, Yankanah R, Wu B, Samson Y, Baruchel S. Phase I study of vinblastine and sirolimus in pediatric patients with[...]
Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: a novel therapeutic agent for neuroblastoma
Eslin D, Sankpal U, Lee C, Sutphin R, Maliakal P, Currier E, Saulnier Sholler G, Khan M, and Basha R.. Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: a novel[...]
A Feasibility Trial using Molecular-Guided Therapy for the Treatment of Patients with Refractory or Recurrent Neuroblastoma
Saulnier Sholler G, Bergendahl G, Vander Werff A, Dutta A, Ferguson W, Roberts W, Eslin D, Kraveka J, Kaplan J, Mitchell D, Parikh N, Neville K, Ashikaga T, Bond J,[...]